Marothi LETSOALO
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Social Risk Phenotypes and the Maternal Burden of Obstetric HIV: A Causal Mixture Modeling Approach

Social Risk Phenotypes
Causal Mixture Modeling
Obstetric HIV
Severe Maternal Outcomes
Latent Classes
Will define the social-risk phenotype framework, baseline covariate structure, and causal mixture modeling strategy for severe maternal outcome analysis in obstetric HIV.
Authors

Marothi Peter Letsoalo

Danielle Jade Roberts

Nonhlanhla Yende-Zuma

Date Updated

March 25, 2026

Keywords

PhDDesk

Focus

Latent social vulnerability structures and their relationship to severe maternal outcomes in obstetric HIV.

Overview

This page will develop the analytical stream that links social determinants, reproductive history, and baseline treatment context to severe maternal outcomes using person-centered mixture models with explicit causal adjustment.

Planned Content

  1. Social and baseline exposure-domain construction.
  2. Phenotype specification and class-evaluation criteria.
  3. Confounding control and weighting strategy.
  4. Distal-outcome modeling and interpretation framework.

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ORCID: 0000-0003-2170-6312

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